منابع مشابه
Dopamine, Striatum, Antipsychotics, and Questions About Weight Gain.
For decades, psychiatrists worried about the adverse motor effects of antipsychotics and tried tounderstandwhat caused them and why some patients developed them and others did not. In the late 1990s, the game changed. The new atypical antipsychotics caused fewer adverse motor effects but causedmoreweight gain. At present, a large number of patients with schizophrenia experience a clinically imp...
متن کاملWeight gain in Asian patients on second-generation antipsychotics.
INTRODUCTION There is increasing evidence that second-generation antipsychotics are associated with weight gain. However almost all available literature has been for Caucasian populations. MATERIALS AND METHODS A health quality improvement project was undertaken at the Institute of Mental Health/Woodbridge Hospital to monitor patients who were started on second-generation antipsychotics. This...
متن کاملWeight gain with antipsychotics: What role does leptin play?
Clinical studies indicate that clozapine and olanzapine carry a high risk of treatment-related metabolic dysfunction—including weight gain, hyperlipidemia, and glucose intolerance—but certain patients with high metabolic liabilities who take atypical antipsychotics do not necessarily develop these adverse effects. Though the underlying mechanism for atypical antipsychotic-related weight gain is...
متن کاملAlmost All Antipsychotics Result in Weight Gain: A Meta-Analysis
INTRODUCTION Antipsychotics (AP) induce weight gain. However, reviews and meta-analyses generally are restricted to second generation antipsychotics (SGA) and do not stratify for duration of AP use. It is hypothesised that patients gain more weight if duration of AP use is longer. METHOD A meta-analysis was conducted of clinical trials of AP that reported weight change. Outcome measures were ...
متن کاملPatterns of Maternal Weight Gain During Pregnancy and Birth Weight
Anthropometric parameters are an important indicator of health and nutritional status comprising the whole span of mans life. However, they are not of the same degree of simplicity and sensitivity in assessing the public health status. During recent decades many studies have attempted to examine the relationships of these measurements in order to present simple alternatives for similar purposes...
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ژورنال
عنوان ژورنال: Science
سال: 2007
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.315.5818.1469b